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Electrophilic Fluorination of Stereodefined Disubstituted Silyl Ketene Hemiaminals en route to Tertiary α-Fluorinated Carbonyl Derivatives | The Nairoukh Research Group

Electrophilic Fluorination of Stereodefined Disubstituted Silyl Ketene Hemiaminals en route to Tertiary α-Fluorinated Carbonyl Derivatives

Citation:

Date Published:

2018

Abstract:

A highly diastereoselective synthesis of tertiary α-fluoro carbonyl compounds is reported in only two chemical steps from a simple alkyne through the reaction of stereodefined fully substituted silyl ketene hemiaminal derivatives with Selectfluor.

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Last updated on 05/19/2021